Platelet Rich Plasma a New Prospective in Treatment of Recalcitrant Erosive Lichen Planus – A Case Report
Sameeulla Shaik *
Department of Oral Medicine and Radiology, CKS Theja Institute of Dental Sciences and Research, Tirupathi, AP -517501, India.
P. Naga Jyothi
Department of Oral Medicine and Radiology, CKS Theja Institute of Dental Sciences and Research, Tirupathi, AP -517501, India.
B. Vijay Kumar
Department of Oral Medicine and Radiology, CKS Theja Institute of Dental Sciences and Research, Tirupathi, AP -517501, India.
S. V. Suman
Department of Oral Medicine and Radiology, CKS Theja Institute of Dental Sciences and Research, Tirupathi, AP -517501, India.
K. Sai Praveen
Department of Oral Medicine and Radiology, CKS Theja Institute of Dental Sciences and Research, Tirupathi, AP -517501, India.
Mercy Sravanthi
Department of Oral Medicine and Radiology, CKS Theja Institute of Dental Sciences and Research, Tirupathi, AP -517501, India.
*Author to whom correspondence should be addressed.
Abstract
Oral lichen planus(OLP) is a chronic disease that worsens the quality of life of patients with risk of malignant potential. Treatment of OLP remains a significant challenge despite the recent advances in understanding the immunopathogenesis. The properties of Platelet-rich plasma (PRP) because of its growth factors, such as epidermal growth factor (EGF), fibroblast growth factor (FGF), Transforming growth factor(TGF β1) and keratinocyte growth factor (KGF) suggested its application in clinical practice for treatment of OLP patients that do not respond to conventional therapy. Hereby we report a case of erosive OLP resistant to conventional therapy efficiently treated with PRP.
Keywords: Oral Lichen Planus, platelet rich plasma, fibroblast growth factor.