Sclerosing Central Mucoepidermoid Carcinoma: Rare Case Series and Review

G. Priyanga *

Department of Oral pathology, Yenepoya Dental College, Derlakatte, Mangalore, Karnataka, India.

Devika Jayarajan

Yenepoya Dental College, Mangalore, Karnataka, India.

Maji Jose

Yenepoya Dental College, Mangalore, Karnataka, India.

Shruthi Nayak

Yenepoya Dental College, Mangalore, Karnataka, India.

*Author to whom correspondence should be addressed.


Abstract

Mucoepidermoid carcinoma (MEC) comprises around 30% of all salivary gland malignancies, making it a preeminent threatening tumour of the salivary glands. Numerous histologic variants with a great extent of separation have been portrayed. Sclerosing MEC (SMEC) has been portrayed as an uncommon subtype, that can be misdiagnosed as a generous receptive condition or low-grade non-SMEC malignancy. The sclerosing variant of central or intraosseous MEC is extremely rare and no cases are reported to date. We report 2 cases of Sclerosing central MEC, in which histologic examination demonstrated relatively nicely-circumscribed, nonencapsulated tumours composed of significant valuable sclerosis and scattered epithelial islands of low-grade MEC. Within the 2nd case, the tumour confirmed comparable sclerotic stroma; but the epithelial component became of intermediate grade. A Mayer mucicarmine stain and PAS stain were fine in each case and discovered plentiful intracytoplasmic mucin. An analysis of sclerosing crucial mucoepidermoid carcinoma was made. A whole resection of the tumour was executed in both instances and remained sickness free to date.

Keywords: Mucoepidermoid carcinoma, sclerosing variant, histopathology, salivary gland


How to Cite

Priyanga, G., Devika Jayarajan, Maji Jose, and Shruthi Nayak. 2022. “Sclerosing Central Mucoepidermoid Carcinoma: Rare Case Series and Review”. International Journal of Research and Reports in Dentistry 5 (2):88-96. https://www.journalijrrd.com/index.php/IJRRD/article/view/106.

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